There is no rule. Using “and” in either case is optional. It’s a matter of writer’s style and context.

Either one is grammatically correct, although names of monuments are captialized. Therefore, write “Leaning Tower of Pisa.”

We wanted to visit some of the key sites in Europe, e.g., the Vatican, the leaning Tower of Pisa, Notre Dame.

Should I be writing:
We wanted to visit some of the key sites in Europe (e.g., the Vatican, the leaning Tower of Pisa, Notre Dame).

The words were underlined for emphasis.
Underlining generally substitutes for italics in a handwritten work.

In your article “e.g.” and “i.e.” seem to be underlined in several places, and in one place “etc.” is underlined. It’s a bit confusing to me what that underlining is indicating. Are you indicating that “e.g” and “i.e.” are to be underlined? or are you highlighting them for some purpose?

This confusion bring up another topic worth clarifying: the use of underlining and italics, especially in relation to word processing tools, and in relation to those of us who frequently use paper and pen and pencil, where italics is not an option.

Thanks for all your good efforts.

This article speaks to the proper use of both parentheses and commas with i.e. and e.g. Otherwise, it depends on the sentence. Please see our posts (All About) Parentheses and Parentheses for more information on when parentheses are appropriate. You will also find our rules for using commas and parentheses helpful.

Thank you for your kind words, Gins, and we send a warm smile back to you.